N-Arachidonoylserotonin (Arachidonyl serotonin; AA-5-HT) is a potent fatty acid amide hydrolase ( FAAH ) inhibitor with an IC 50 value of 1~12 µM. N-Arachidonoylserotonin acts also as an antagonist of transient receptor potential vanilloid-type 1 (TRPV1) channels (IC 50 =70~100 nM). N-Arachidonoylserotonin is analgesic in rodents .
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