ZJ43

Overview

ZJ43 is a NAAG peptidase inhibitor and glutamate carboxypeptidase II / III ( GCP II/III ) inhibitor with human GCP II IC 50 of 2.4 nM and K i of 0.8 nM. ZJ43 blocks N-acetylaspartylglutamate hydrolysis, elevates extracellular N-acetylaspartylglutamate levels, and activates group II metabotropic glutamate receptors ( mGluR ). ZJ43 can be used for the research of schizophrenia, inflammatory pain, neuropathic pain, and traumatic brain injury.

Application

Products | Products > Disease Areas > Schizophrenia | Products > Disease Areas > Pain | Products > Disease Areas > Traumatic Brain Injury | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Nervous System Injury | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Aminopeptidase | Products > Signaling Pathways > Carboxypeptidase | Products > Signaling Pathways > mGluR

Product Information

• Catalog No.: HY-103344
• CAS No.: 723331-20-2
• Molecular Formula: C12H20N2O7
• Molecular Weight: 304.30
• Purity: 99.6%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source