SID 26681509

Overview

SID 26681509 is a potent, reversible, competitive, and selective inhibitor of human cathepsin L with an IC 50 of 56 nM. SID 26681509 inhibits in vitro propagation of malaria parasite Plasmodium falciparum and inhibits Leishmania major with IC 50 s of 15.4 μM and 12.5 μM, respectively. SID 26681509 shows no inhibitory activity against cathepsin G.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Cancer | Products > Disease Areas > Parasitic Infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Infection | Products > Signaling Pathways > Cathepsin | Products > Signaling Pathways > Parasite

Product Information

• Catalog No.: HY-103353
• CAS No.: 958772-66-2
• Molecular Formula: C27H33N5O5S
• Molecular Weight: 539.65
• Purity: 99.16%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 1.25 mg/mL (2.32 mM); Clear solution
• Availability: In-stock

Source

Original product source