PG01

Overview

PG01 is a potent CFTR Cl - channel potentiator. PG01 can correct gating defects of CFTR mutants, is effective on b>E193K, G970R and G551D ( CFTR mutants) with K d values of 0.22 μM, 0.45 μM and 1.94 μM, respectively. PG01 is also effective on ΔF508 ( K a of 0.3 μM). PG01 increases ΔF508-CFTR Cl - current after adding Forskolin.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Endocrinology | Products > Signaling Pathways > CFTR

Product Information

• Catalog No.: HY-103369
• CAS No.: 853138-65-5
• Molecular Formula: C28H29N3O2
• Molecular Weight: 439.55
• Purity: 98.04%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source