2'-Deoxyuridine

Overview

2’-deoxyuridine is a brain-penetrant pyrimidines nucleotide that is associated with nervous system diseases. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. 2'-Deoxyuridine is a precursor in the synthesis of Edoxudine ( HY-B1011 ) and also an analogue of 5-ethynyl-2'-deoxyuridine, EdU ( HY-118411 ). 2’-deoxyuridine reduces microglial activation and improve oxidative stress damage by modulating glycolytic metabolism on the Aβ25-35-induced brain injury, which is promising for research of Alzheimer’s disease (AD).

Application

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Product Information

• Catalog No.: HY-D0186
• CAS No.: 951-78-0
• Molecular Formula: C9H12N2O5
• Molecular Weight: 228.20
• Purity: 99.98%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.08 mg/mL (9.11 mM); Clear solution
• Availability: In-stock

Source

Original product source