THAM

Overview

THAM (Tris) is a low-toxicity amino alcohol buffer, a specific CO 2 -consuming proton acceptor that buffers carbon dioxide and acid both in vitro and in vivo. THAM binds protons to form bicarbonate, reduces PaCO 2 , and induces intracellular alkalization, thereby ameliorating hypercapnia-induced elevation of pulmonary blood vessels and pulmonary arterial pressure. THAM may cause PaCO 2 rebound, hypoglycemia, and respiratory depression. THAM removes amniotic epithelium and preserves the basement membrane, but depletes extracellular matrix and reduces the adhesion rate of limbal epithelial cells. THAM can act as a CO 2 carrier to enhance the productivity and carbon utilization rate of Scenedesmus obliquus . THAM is a key component of buffer solutions used in various biological, cell culture , biochemical, and molecular biology applications.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Others | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Biochemical Assay Reagents

Product Information

• Catalog No.: HY-D0227
• CAS No.: 77-86-1
• Molecular Formula: C4H11NO3
• Molecular Weight: 121.14
• Purity: 99.88%
• Storage: Store at room temperature, keep dry and cool. In solvent -80°C, 1 year , -20°C, 6 months
• Availability: In-stock

Source

Original product source