Glycylglycine

Overview

Glycylglycine is a non-selective glycylglycine dipeptidase substrate and iNOS inhibitor. Glycylglycine can cross the cell membrane by passive diffusion and is hydrolyzed to glycine in the cell, participating in energy metabolism and antioxidant processes. Glycylglycine promotes spermatogonial stem cells (SSCs) proliferation, inhibits astrocyte overactivation and reduces nitric oxide (NO) release, while upregulating the expression of neurotrophic factors (such as PDGFA, FGF2, CNTF ) to support nerve myelin repair. Glycylglycine can be used to study male reproductive biology (such as SSCs proliferation regulation) and neurodegenerative diseases (such as neuroprotective mechanisms in multiple sclerosis).

Application

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Product Information

• Catalog No.: HY-D0889
• CAS No.: 556-50-3
• Molecular Formula: C4H8N2O3
• Molecular Weight: 132.12
• Purity: 99.90%
• Storage: RT, protect from light. In solvent -80°C, 1 year , -20°C, 6 months
• Solubility: 100 mg/mL (756.89 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source