SSR69071 is a potent, orally active and selective inhibitor of neutrophil elastase . SSR69071 reduces myocardial infarct size following ischemia-reperfusion injury. SSR69071 displays a higher affinity for human elastase (K i =0.0168 nM) than for rat (K i =3 nM), mouse (K i =1.8 nM), and rabbit (K i = 58 nM) elastases.
Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Cardiovascular Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Elastase
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