EDTA-AM

Overview

EDTA-AM (ethylenediaminetetraacetic acid, acetoxymethyl ester) is the membrane-permeant form of the metal chelator EDTA ( HY-Y0682 ). Live cells passively load EDTA-AM by incubating with EDTA-AM. Once internalized, cytoplasmic esterase decomposes AM esters, releasing the active ligand EDTA, which isolates metal ions within the cell. EDTA-AM induces an arrest of mitotic progression and chromosome decondensation.

Application

Products | Products > Disease Areas > Others | Products > Signaling Pathways > Others | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Others | Products > Signaling Pathways > Biochemical Assay Reagents | Products > Signaling Pathways > Mitosis

Product Information

• Catalog No.: HY-D1746
• CAS No.: 162303-59-5
• Molecular Formula: C22H32N2O16
• Molecular Weight: 580.49
• Purity: 98.0%
• Storage: -20°C, protect from light, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
• Availability: In-stock

Source

Original product source