BODIPY-FL staurosporine (Compound 8a) is a fluorescence probe based on staurosporine, exhibiting high specificity towards tyrosine kinases ( TK ) and tyrosine kinase-like ( TKL ) family kinases. BODIPY-FL staurosporine has the potential to develop binding assays for kinases that are not recommended for use with Kinase Tracer 236, such as PIM3 , CDC42BPG, MAP2K7, TXK, and SIK3 . BODIPY-FL staurosporine can be a powerful tool for analyzing kinase selectivity in kinase drug discovery.
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