NNC 05-2090 hydrochloride is a GABA uptake inhibitor and inhibitor of the β-GABA transporter ( BGT-1 ) ( IC 50< /sub> : 10.6 μM). NNC 05-2090 hydrochloride also inhibits mGAT2 with a K i value of 1.4 μM. NNC 05-2090 has anticonvulsant activity and can be used in the study of epilepsy and neurological diseases.
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