Omeprazole sulfone- 13 C,d 3

Overview

Omeprazole sulfone- 13 C,d 3 is the deuterium and 13 C labeled Omeprazole sulfone. Omeprazole sulfone (Omeprazole sulphone) is one of the major circulating metabolites of Omeprazole ( HY-B0113 ) in vivo, and belongs to class 4 non-mutagenic impurities. Omeprazole sulfone does not bind to the aryl hydrocarbon receptor ( AhR ), nor does it induce the expression of CYP1A1 or CYP1A2 . However, Omeprazole sulfone promotes the migration of gastric epithelial cells under basal conditions and reverses the inhibitory effect of Indomethacin ( HY-14397 ) on cell migration. Omeprazole sulfone does not promote cell proliferation, nor does it upregulate COX-2 expression or activate signaling pathways such as ERK , P38 MAPK and PI3K . Omeprazole sulfone maintains basal ulcer healing under non-acid-dependent conditions and can be used in studies related to gastric ulcer repair.

Application

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Product Information

• Catalog No.: HY-G0007S1
• CAS No.: 1261393-28-5
• Molecular Formula: C1613CH16D3N3O4S
• Molecular Weight: 365.43
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source