(-)-Epicatechin- 13 C 3 ((-)-Epicatechol- 13 C 3 ) is 13 C labeled (-)-Epicatechin. (-)-Epicatechin inhibits cyclooxygenase-1 ( COX-1 ) with an IC 50 of 3.2 μM. (-)-Epicatechin inhibits the IL-1β-induced expression of iNOS by blocking the nuclear localization of the p65 subunit of NF-κB .
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