Inosine (Standard)

Overview

Inosine (Standard) is the analytical standard of Inosine. This product is intended for research and analytical applications. Inosine is an endogenous purine nucleoside produced by catabolism of adenosine. Inosine has anti-inflammatory, antinociceptive, immunomodulatory and neuroprotective effects. Inosine is an agonist for adenosine A 1 ( A 1 R ) and A 2A ( A 2A R ) receptors. In Vitro: Inosine dose-dependently stimulates cAMP production mediated through the A 2A R. Inosine dose-dependently induces hA 2A R-mediated ERK1/2 phosphorylation. Inosine (100 μM; 24 hours) reduces oxidative stress in MES 23.5 cells cultured with astrocytes. In Vivo: Inosine (10-100 mg/kg; i.p.) exhibits antinociceptive effect in mice.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Others | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > Adenosine Receptor | Products > Signaling Pathways > Endogenous Metabolite

Product Information

• Catalog No.: HY-N0092R
• CAS No.: 58-63-9
• Molecular Formula: C10H12N4O5
• Molecular Weight: 268.23
• Purity: 99.93%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source