Palmatine chloride

Overview

Palmatine chloride is an orally active and irreversible indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor with IC 50 s of 3 μM and 157μM against HEK 293-hIDO-1 and rhIDO-1, respectively. Palmatine chloride can also inhibit West Nile virus (WNV) NS2B-NS3 protease in an uncompetitive manner with an IC 50 of 96 μM. Palmatine chloride shows anti-cancer, anti-oxidation, anti-inflammatory, neuroprotection, antibacterial , anti-viral activities.

Application

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Product Information

• Catalog No.: HY-N0110
• CAS No.: 10605-02-4
• Molecular Formula: C21H22ClNO4
• Molecular Weight: 387.86
• Purity: 99.87%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 1 year; -20°C, 6 months (sealed storage, away from moisture and light)
• Solubility: ≥ 2.5 mg/mL (6.45 mM); Clear solution
• Availability: In-stock

Source

Original product source