Tetrahydropapaverine hydrochloride

Overview

Tetrahydropapaverine hydrochloride is a tetrahydroisoquinoline (TIQ) compound with inhibitory effects on tryptophan hydroxylase ( TPH ) ( IC 50 = 5.7 μM). Tetrahydropapaverine hydrochloride decreases intracellular serotonin content in murine mastocytoma P815 cells, with an IC 50 value of 6.2 μM. Tetrahydropapaverine hydrochloride can be used for studies on potential neurotoxicity in monoaminergic neurons.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Tryptophan Hydroxylase

Product Information

• Catalog No.: HY-N0137
• CAS No.: 6429-04-5
• Molecular Formula: C20H26ClNO4
• Molecular Weight: 379.88
• Purity: 99.08%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.5 mg/mL (6.58 mM); Clear solution
• Availability: In-stock

Source

Original product source