Orotic acid- 13 C, 15 N 2 monohydrate

Overview

Orotic acid- 13 C, 15 N 2 (monohydrate) is the 13 C and 15 N labeled Orotic acid. Orotic acid (6-Carboxyuracil), a precursor in biosynthesis of pyrimidine nucleotides and RNA, is released from the mitochondrial dihydroorotate dehydrogenase (DHODH) for conversion to UMP by the cytoplasmic UMP synthase enzyme. Orotic acid is a marker for measurement in routine newborn screening for urea cycle disorders. Orotic acid can induce hepatic steatosis and hepatomegaly in rats.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Nucleoside Antimetabolite/Analog | Products > Signaling Pathways > Endogenous Metabolite

Product Information

• Catalog No.: HY-N0157S1
• CAS No.: 1346602-15-0
• Molecular Formula: C413CH615N2O5
• Molecular Weight: 177.09
• Purity: 99.93%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source