Saikosaponin B2

Overview

Saikosaponin B2 is an antiviral and anticancer agent that regulates multiple transporters (such as various solute carriers and ATP-binding cassette transporters including MRP1 , MRP2 , and OCT2 ). Saikosaponin B2 is isolated from the plant glycoside component of the roots of Bupleurum scorzonerifolium . Saikosaponin B2 enhances the liver targeting of anticancer drugs via vinegar-baked Radix Bupleuri. Saikosaponin B2 inhibits HCV entry, replication, and translation, is effective against Daclatasvir ( HY-10466 )-resistant strains, and exerts a synergistic effect when used in combination with Daclatasvir . Saikosaponin B2 is commonly used in studies related to hepatocellular carcinoma and HCV infection .

Application

Products | Products > Disease Areas > Liver Cancer | Products > Disease Areas > Digestive System Cancer | Products > Disease Areas > Hepatitis C Virus Infection | Products > Disease Areas > Cancer | Products > Disease Areas > Infection | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Hepatitis Virus Infection | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Infection | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > HCV | Products > Signaling Pathways > P-glycoprotein

Product Information

• Catalog No.: HY-N0248
• CAS No.: 58316-41-9
• Molecular Formula: C42H68O13
• Molecular Weight: 780.98
• Purity: 99.98%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.5 mg/mL (3.20 mM); Clear solution
• Availability: In-stock

Source

Original product source