Hederagenin (Standard)

Overview

Hederagenin (Standard) is the analytical standard of Hederagenin. This product is intended for research and analytical applications. Hederagenin is a triterpenoid saponin with orally active and antitumor activity. Hederagenin can inhibit the expression of iNOS , COX-2 , and NF-κB in cells induced by LPS stimulation. Hederagenin also increases ROS production in cancer cells, disrupts mitochondrial membrane potential, and induces apoptosis . Hederagenin also sensitizes cancer cells to Cisplatin ( HY-17394 ) and Paclitaxel ( HY-B0015 ), enhancing induced apoptosis . Hederagenin also has preventive potential against alcoholic liver injury.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Others | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > NF-κB | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > COX | Products > Signaling Pathways > NF-κB

Product Information

• Catalog No.: HY-N0256R
• CAS No.: 465-99-6
• Molecular Formula: C30H48O4
• Molecular Weight: 472.70
• Purity: 99.84%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source