4-Methoxycinnamic acid ethyl ester

Overview

4-Methoxycinnamic acid ethyl ester (Ethyl p-methoxycinnamate) is an orally active natural compound found. 4-Methoxycinnamic acid ethyl ester exerts anti-inflammatory effects by inhibiting cyclooxygenase ( COX-1 ( IC 50 = 1.12 μM) and COX-2 ( IC 50 = 0.83 μM)), NF-κB ( IC 50 = 88.7 μM) and cytokine production ( TNF-α ( IC 50 = 96.84 μg/mL) and IL-1β ( IC 50 = 166.4 μg/mL)). 4-Methoxycinnamic acid ethyl ester inhibits tumor cell proliferation, migration and cancer metabolism and induces apoptosis .4-Methoxycinnamic acid ethyl ester inhibits VEGF expression, thereby inhibiting angiogenesis. 4-Methoxycinnamic acid ethyl ester has a significant inhibitory effect on dengue virus and Mycobacterium tuberculosis. 4-Methoxycinnamic acid ethyl ester has analgesic effects in rats.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Infection | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Neurological Disease | Products > Research Areas > Metabolic Disease | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Infection | Products > Research Areas > Cardiovascular Disease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Interleukin Related | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > VEGFR | Products > Signaling Pathways > Bacterial | Products > Signaling Pathways > Dengue Virus | Products > Signaling Pathways > Caspase | Products > Signaling Pathways > COX | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > TNF Receptor

Product Information

• Catalog No.: HY-N0346
• CAS No.: 1929-30-2
• Molecular Formula: C12H14O3
• Molecular Weight: 206.24
• Purity: 98.72%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Solubility: ≥ 2.5 mg/mL (12.12 mM); Clear solution
• Availability: In-stock

Source

Original product source