(+)-Columbianetin (Standard) is the analytical standard of (+)-Columbianetin ( HY-N0363 ). This product is intended for research and analytical applications. (+)-Columbianetin ((S)-Columbianetin) acts as an inhibitor of JNK / ERK . (+)-Columbianetin inhibits UVA-induced phosphorylation of JNK and ERK , reduces the production of MMP-1 , reverses UVA-induced Collagen ( HY-NP003 ) degradation, and alleviates UVA-mediated inhibition of Smad2/3 phosphorylation and translocation. (+)-Columbianetin regulates the AP-1 and ASK1-MAPK signaling pathways, inhibits the production of ROS and blocks sub-G 1 cell cycle arrest. (+)-Columbianetin is applicable to research related to skin aging.
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