Escin IA is an oral LOXL2 inhibitor and EMT inhibitor, with selectivity for LOXL2 -expressing cells. Escin IA suppresses invasion, migration, and metastasis of breast cancer cells, and acts as the primary anti-TNBC metastasis constituent of Aesculus chinensis Bunge fruit saponin fraction. Escin IA can be used for the research of triple-negative breast cancer , acute inflammation, and ethanol-induced gastric mucosal lesions.
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