Canertinib dihydrochloride

Overview

Canertinib dihydrochloride (CI-1033 dihydrochloride) is a potent and irreversible EGFR inhibitor; inhibits cellular EGFR and ErbB2 autophosphorylation with IC 50 s of 7.4 and 9 nM. Canertinib dihydrochloride is active against vaccinia virus respiratory infection in mice.

Application

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Product Information

• Catalog No.: HY-10367A
• CAS No.: 289499-45-2
• Molecular Formula: C24H27Cl3FN5O3
• Molecular Weight: 558.86
• Purity: 99.68%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.08 mg/mL (3.72 mM); Clear solution
• Availability: In-stock

Source

Original product source