Mulberroside C

Overview

Mulberroside C is one of the main bioactive components in white mulberry ( Morus alba L. ). Mulberroside C exhibits antiplatelet, antiviral and neutrophil-regulating activities, and binds to EV-A71 VP1 with a K d value of 1.289 nM. Mulberroside C reduces the phosphorylation level of ERK , promotes the phosphorylation of IP3RI at the Ser 1756 site, and decreases calcium influx and calcium mobilization. Mulberroside C inhibits the expression of P-selectin ( P-selectin ). Mulberroside C upregulates the cyclic nucleotide signaling pathway in human platelets. Mulberroside C binds to IL-23R , upregulates the expression of G-CSF , GM-CSF and RASGRP1 , and activates the RAS / ERK signaling pathway. Mulberroside C promotes neutrophil maturation, accelerates the recovery of leukopenia, and enhances the antibacterial activity of neutrophils. Mulberroside C inhibits the replication of hepatitis C virus in replicon cells. Mulberroside C prevents the uncoating and genome release of EV-A71 , and inhibits the synthesis of viral proteins and RNA. Mulberroside C can be used in studies related to thrombosis-mediated cardiovascular diseases, chemotherapy- and radiotherapy-induced leukopenia, hepatitis C virus infection , and hand, foot and mouth disease.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Hepatitis Virus Infection | Products > Disease Areas > Bacterial Infection | Products > Disease Areas > Hepatitis C Virus Infection | Products > Disease Areas > Staphylococcus Aureus Infection | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Stem Cell/Wnt | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Infection | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > HCV | Products > Signaling Pathways > Enterovirus | Products > Signaling Pathways > PERK | Products > Signaling Pathways > Calcium Channel | Products > Signaling Pathways > P-selectin | Products > Signaling Pathways > HCN Channel | Products > Signaling Pathways > Ras | Products > Signaling Pathways > ERK | Products > Signaling Pathways > DNA/RNA Synthesis

Product Information

• Catalog No.: HY-N0620
• CAS No.: 102841-43-0
• Molecular Formula: C24H26O9
• Molecular Weight: 458.46
• Purity: 99.77%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.5 mg/mL (5.45 mM); Clear solution
• Availability: In-stock

Source

Original product source