Cornuside (Standard)

Overview

Cornuside (Standard) is the analytical standard of Cornuside ( HY-N0631 ). This product is intended for research and analytical applications. Cornuside is an iridoid glycoside with anti-allergic, anti-inflammatory, and neuroprotective activities. Cornuside exerts anti-allergic activity by downregulating the p38 MAPK , JNK , and NF-κB signaling pathways, and inhibits IgE-mediated histamine release from mast cells. Cornuside improves cognitive impairment in mice by inhibiting BACE1 activity ( IC 50 = 55.84 μg/mL) and enhancing ChAT activity. Cornuside inhibits LPS ( HY-D1056 )-induced inflammatory mediators, including iNOS , COX-2 , PGE2 , TNF-α , IL-6 , and IL-1β , by suppressing NF-κB activation.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Others | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > NO Synthase | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > p38 MAPK | Products > Signaling Pathways > COX | Products > Signaling Pathways > JNK | Products > Signaling Pathways > ERK | Products > Signaling Pathways > TNF Receptor | Products > Signaling Pathways > Interleukin Related | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Prostaglandin Receptor | Products > Signaling Pathways > Acyltransferase | Products > Signaling Pathways > Cholinesterase (ChE)

Product Information

• Catalog No.: HY-N0631R
• CAS No.: 131189-57-6
• Molecular Formula: C24H30O14
• Molecular Weight: 542.49
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source