(±)-Eriodictyol (Standard)

(±)-Eriodictyol (Standard)
  • CAS No.:4049-38-1
  • Grade:98%
  • Formula:C15H12O6
  • M.W.:288.25

Overview

3-Chlorobenzoic acid (Standard) is the analytical standard of 3-Chlorobenzoic acid. This product is intended for research and analytical applications. (±)-Eriodictyol ((±)-Huazhongilexone; Dihydroluteolin) is an orally active TRPV1 receptor antagonist ( IC 50 =44-47 nM, rTRPV1 ) with antioxidant and anti-inflammatory activities. (±)-Eriodictyol effectively inhibits lipid peroxidation and the release of proinflammatory cytokines by specifically antagonizing the TRPV1 receptor and activating the Nrf2 signaling pathway. (±)-Eriodictyol reduces the levels of ICAM-1, VEGF , eNOS and TNF-α in the retina and maintains the integrity of the blood-retinal barrier. (±)-Eriodictyol alleviates oxidative stress-induced apoptosis and hyperalgesia, enhances the activity and cytotoxicity of immune cells (such as B lymphocytes, NK cells and macrophages), and increases the levels of antioxidant enzymes simultaneously. (±)-Eriodictyol can be used in the research of diabetic retinopathy, acute lung injury and various pain-related diseases.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Others | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > Melanocortin Receptor | Products > Signaling Pathways > TRP Channel

Product Information

  • Catalog No.: HY-N0637AR
  • CAS No.: 4049-38-1
  • Molecular Formula: C15H12O6
  • Molecular Weight: 288.25
  • Purity: 98%
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
  • Availability: In-stock

Source

Original product source


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