N-Ac-γ-Calicheamicin-AcBut-NHS ester

Overview

AcBut-N-Ac-γ-Calicheamicin is an ADC cytotoxic payload that induces cell cycle arrest and apoptosis by causing DNA double-strand breaks. AcBut-N-Ac-γ-Calicheamicin is primarily used in the synthesis of antibody-drug conjugates ( ADC ) and holds promise for research in the field of cancer , including acute lymphoblastic leukemia (ALL) and other hematological malignancies.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Antibody-Drug Conjugate/ADC Related | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Signaling Pathways > ADC Payloads

Product Information

• Catalog No.: HY-103688
• CAS No.: 174885-02-0
• Molecular Formula: C77H99IN6O28S3
• Molecular Weight: 1779.73
• Purity: 95.62%
• Storage: -20°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Availability: In-stock

Source

Original product source