Schisantherin B (Gomisin-B) (Standard) is the analytical standard of Schisantherin B. This product is intended for research and analytical applications. Schisantherin B is a lignan compound and one of the active components of Schisandra chinensis. Schisantherin B activates the PI3K / AKT signaling pathway, restores the activity of GSK3β , and reduces the hyperphosphorylation of tau protein in hippocampal and cerebral cortical tissues. Schisantherin B upregulates the level of GLT-1 , decreases the expression of pro-inflammatory cytokines TNF-α/IL-1β/IL-6 , upregulates the expression of IL-10 , and inhibits cell apoptosis . Schisantherin B is applicable to the research of spinal cord injury, Alzheimer's disease and depression.
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