Isomangiferin

Overview

Isomangiferin is an orally active xanthone C-glucoside, and its chemical structure is similar to Mangiferin ( HY-N0290 ). Isomangiferin is an effective VEGFR-2 kinase inhibitor, which can induces cell apoptosis , inhibit the growth, metastasis and angiogenesis of breast cancer . Isomangiferin exerts anti-inflammatory effects by inhibiting the HMGB1/NLRP3/NF-κB signaling pathway, thereby improving the renal function indicators of diabetic mice. Isomangiferin exhibits inhibitory effects on various bacteria and herpes simplex virus type 1 ( HSV-1 ). Isomangiferin promotes the migration and osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) and reduces cell apoptosis and the production of ROS by activating the AMPK/ACC pathway, thereby facilitating fracture healing.

Application

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Product Information

• Catalog No.: HY-N0772
• CAS No.: 24699-16-9
• Molecular Formula: C19H18O11
• Molecular Weight: 422.34
• Purity: 99.60%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.5 mg/mL (5.92 mM); Clear solution
• Availability: In-stock

Source

Original product source