Chikusetsusaponin Iva

Overview

Chikusetsusaponin IVa is an orally active protein kinase activator. Chikusetsusaponin IVa binds to YAP with a K D value of 0.388 mM. Chikusetsusaponin IVa reduces inflammatory mediators ( IL-6 , IL-10 , COX-2 ) expression, NO production, promotes ROS generation, induces Apoptosis , inhibits MAPK , TAZ , and regulates Nrf2 , JAK/STAT . Chikusetsusaponin Iva has anti- H9N2 AIV and anti-endometrial cancer activities. Chikusetsusaponin Iva shows anti-inflammatory, hepatoprotective and osteoprotective effects.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Colorectal Cancer | Products > Disease Areas > Digestive System Cancer | Products > Disease Areas > Prostate Cancer | Products > Disease Areas > Urogenital Cancer | Products > Disease Areas > Ovarian Cancer | Products > Disease Areas > Depression | Products > Disease Areas > Pain | Products > Disease Areas > Cancer | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Infection | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > NF-κB | Products > Research Areas > Metabolic Disease | Products > Research Areas > Infection | Products > Research Areas > Endocrinology | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Keap1-Nrf2

Product Information

• Catalog No.: HY-N0818
• CAS No.: 51415-02-2
• Molecular Formula: C42H66O14
• Molecular Weight: 794.97
• Purity: 99.61%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (3.14 mM); Clear solution
• Availability: In-stock

Source

Original product source