Alisol A 24-acetate

Overview

Alisol A 24-acetate (Alisol A monoacetate) is an orally active derivative of protostane-type tetracyclic triterpenoid. Alisol A 24-acetate upregulates the expression of adiponectin , AMPKα , CPT1 , and ACOX1 ; downregulates the expression of SREBP-1c , ACC , FAS , Bcl-2 , Bcl-xl , PPAR-γ , perilipin A , and NFATc1 ; inhibits the activity of PI3K/Akt/mTOR and HMGR ; and activates the PKA and ERK signaling pathways. Alisol A 24-acetate regulates cell apoptosis ( apoptosis ), autophagy ( Autophagy , hepatic lipid accumulation, inflammatory response, neuroprotection, MRSA membrane integrity, and osteoclast differentiation. Alisol A 24-acetate can be used in research related to non-alcoholic fatty liver disease, nephrotoxicity, obesity, global cerebral ischemia-reperfusion injury, bacterial infection , and osteoporosis.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Lipid Metabolism | Products > Disease Areas > Mineral Metabolism | Products > Disease Areas > Bacterial Infection | Products > Disease Areas > Cerebrovascular Disease | Products > Disease Areas > Renal Disease | Products > Disease Areas > Obesity | Products > Disease Areas > Fatty Liver Disease | Products > Disease Areas > Osteoporosis | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Vitamin D Related/Nuclear Receptor | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > TGF-beta/Smad | Products > Research Areas > Neurological Disease | Products > Research Areas > Metabolic Disease | Products > Research Areas > Infection | Products > Research Areas > Endocrinology | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > AMPK | Products > Signaling Pathways > Carnitine Palmitoyltransferase (CPT) | Products > Signaling Pathways > Acyltransferase | Products > Signaling Pathways > Fatty Acid Synthase (FASN) | Products > Signaling Pathways > Acetyl-CoA Carboxylase | Products > Signaling Pathways > Bcl-2 Family | Products > Signaling Pathways > PPAR | Products > Signaling Pathways > Nuclear Factor of activated T Cells (NFAT) | Products > Signaling Pathways > PI3K | Products > Signaling Pathways > Akt | Products > Signaling Pathways > PKA | Products > Signaling Pathways > ERK | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Autophagy

Product Information

• Catalog No.: HY-N0853A
• CAS No.: 18674-16-3
• Molecular Formula: C32H52O6
• Molecular Weight: 532.75
• Purity: 98.0%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 3 mg/mL (5.63 mM); Clear solution
• Availability: In-stock

Source

Original product source