Alisol F

Overview

Alisol F is a protostane-type triterpenoid with anti-inflammatory and anti-hepatitis B virus activities. Alisol F inhibits LPS ( HY-D1056 )-induced phosphorylation of ERK , JNK , p38 , STAT3 and NF-κB (p65), suppresses the production of NO , IL-6 , TNF-α and IL-1β , and also downregulates the levels of iNOS and COX-2 . Alisol F reduces the serum alanine aminotransferase and aspartate aminotransferase levels in mice with acute liver injury and ameliorates their liver pathological damage.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Liver Cancer | Products > Disease Areas > Digestive System Cancer | Products > Disease Areas > Liver Disease | Products > Disease Areas > Hepatitis B Virus Related Hepatocellular Carcinoma | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Metabolic Disease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > ERK | Products > Signaling Pathways > JNK | Products > Signaling Pathways > p38 MAPK | Products > Signaling Pathways > STAT | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > TNF Receptor | Products > Signaling Pathways > Interleukin Related | Products > Signaling Pathways > NO Synthase | Products > Signaling Pathways > COX | Products > Signaling Pathways > HBV

Product Information

• Catalog No.: HY-N0854
• CAS No.: 155521-45-2
• Molecular Formula: C30H48O5
• Molecular Weight: 488.70
• Purity: 99.89%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (5.12 mM); Clear solution
• Availability: In-stock

Source

Original product source