Aloin B (Standard)

Overview

Aloin B (Isobarbaloin) (Standard) is the analytical standard of Aloin B. This product is intended for research and analytical applications. Aloin B is an orally active SARS-CoV-2 papain-like protease ( PLpro ) inhibitor with an IC 50 of 16.08 μM (hydrolytic activity) and 17.51 μM ( deubiquitinase activity). Aloin B is metabolized by rat intestinal flora into aloe-emodin-9-anthrone to exert laxative effects. Aloin B inhibits TPA ( HY-18739 )-induced ear edema, putrescine elevation, and tumor promotion in mouse skin. Aloin B can be used in research related to anti-inflammation, tumor promotion inhibition, coronavirus disease 2019 (COVID-19) and constipation.

Application

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Product Information

• Catalog No.: HY-N0886R
• CAS No.: 28371-16-6
• Molecular Formula: C21H22O9
• Molecular Weight: 418.39
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source