PTP1B-IN-20 is a selective inhibitor of protein tyrosine phosphatase 1B ( PTP1B ; IC 50 =1.05 μM) over the highly homologous T-cell protein tyrosine phosphatase ( TCPTP ; IC 50 =78.0 μM), which is a key target for type 2 diabetes inhibition.
Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Phosphatase
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