Tremulacin

Overview

Tremulacin is a 5-LOX inhibitor. Tremulacin reduces the biosynthesis of LTB 4 and slow-reacting substances of anaphylaxis. Tremulacin alleviates carrageenan-induced paw edema in rats, croton oil-induced ear edema in mice, and acetic acid-induced writhing response in mice. Tremulacin inhibits TNF-α-stimulated ROS production and MMP-1 expression, and promotes collagen secretion in human dermal fibroblasts. Tremulacin is investigated for studies on inflammation-related diseases.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Lipoxygenase | Products > Signaling Pathways > Leukotriene Receptor | Products > Signaling Pathways > Reactive Oxygen Species (ROS) | Products > Signaling Pathways > MMP

Product Information

• Catalog No.: HY-N11072
• CAS No.: 29836-40-6
• Molecular Formula: C27H28O11
• Molecular Weight: 528.50
• Purity: 96.41%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (4.73 mM); Clear solution
• Availability: In-stock

Source

Original product source