Tetrahydroalstonine

Overview

Tetrahydroalstonine ((-)-Tetrahydroalstonine) is an indole alkaloid and a selective α₂-adrenergic receptor antagonist. Tetrahydroalstonine exhibits certain neuroprotective effects. Tetrahydroalstonine can regulate autophagy-lysosomal function by activating the Akt/mTOR pathway, significantly reducing OGD/R-induced primary cortical neuronal injury.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Neurological Disease | Products > Research Areas > Endocrinology | Products > Signaling Pathways > Adrenergic Receptor | Products > Signaling Pathways > Atg8/LC3 | Products > Signaling Pathways > Akt | Products > Signaling Pathways > mTOR

Product Information

• Catalog No.: HY-N1163
• CAS No.: 6474-90-4
• Molecular Formula: C21H24N2O3
• Molecular Weight: 352.43
• Purity: 99.84%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Availability: In-stock

Source

Original product source