Panduratin A

Overview

Panduratin A is an orally active natural compound with multiple pharmacological activities. By specifically inhibiting the NF-κB signaling pathway, Panduratin A exerts potent anti-inflammatory and antioxidant effects in intestinal and vascular inflammation models. Panduratin A exerts a definite protective effect against Colistin ( HY-113678 )-induced nephrotoxicity by alleviating oxidative stress, improving mitochondrial dysfunction and inhibiting cell apoptosis . Panduratin A activates autophagy via an AMPK -dependent pathway and exhibits anti-tuberculosis activity. Panduratin A exerts antiviral effects by inhibiting the methyltransferase ( DNA Methyltransferase ) of SARS-CoV-2.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Coronavirus Infection | Products > Disease Areas > Renal Disease | Products > Disease Areas > SARS-CoV-2 Infection | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Infection | Products > Research Areas > Endocrinology | Products > Signaling Pathways > Keap1-Nrf2 | Products > Signaling Pathways > AMPK | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > SARS-CoV | Products > Signaling Pathways > DNA Methyltransferase | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > NF-κB

Product Information

• Catalog No.: HY-N11722
• CAS No.: 89837-52-5
• Molecular Formula: C26H30O4
• Molecular Weight: 406.51
• Purity: 99.9%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source