Catenarin

Overview

Catenarin, an anthraquinone compound, inhibits CCR5 - and CXCR4 -mediated chemotaxis. Catenarin reduces the phosphorylation of mitogen-activated protein kinases ( p38 and JNK ) and their upstream kinases ( MKK6 and MKK7 ), and calcium mobilization. Catenarin shows anti-inflammatory effect and suppresses leukocyte migration in the diabetes. Catenarin exhibits significant inhibitory effects against Gram-positive bacteria. Catenarin prevents type 1 diabetes (T1D) in nonobese diabetic mice [1][2] .

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Metabolic Disease | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Infection | Products > Signaling Pathways > JNK | Products > Signaling Pathways > Calcium Channel | Products > Signaling Pathways > CCR | Products > Signaling Pathways > CXCR | Products > Signaling Pathways > p38 MAPK

Product Information

• Catalog No.: HY-N11723
• CAS No.: 476-46-0
• Molecular Formula: C15H10O6
• Molecular Weight: 286.24
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source