12-O-Tiglyl-phorbol 13-dodecanoate

Overview

12-O-Tiglyl-phorbol 13-dodecanoate (TD13) is a potential inhibitor with anti-hepatic fibrosis activity, and it belongs to a series of derivatives of oral APOL2 inhibitors and anti-hepatic fibrosis agents. It shows no obvious toxicity in preclinical models. Compounds of the 12-O-Tiglyl-phorbol 13-dodecanoate series inhibit the expression of fibronectin, type I collagen and α- smooth muscle actin in hepatic stellate cells. 12-O-Tiglyl-phorbol 13-dodecanoate can be isolated from the Euphorbiaceae plant Euphorbia fischeriana , and it is applicable to the research of hepatic fibrosis.

Application

Products | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Liver Disease | Products > Disease Areas > Hepatic Fibrosis | Products > Signaling Pathways > Cytoskeleton | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Collagen

Product Information

• Catalog No.: HY-N11736
• CAS No.: 37394-32-4
• Molecular Formula: C37H56O8
• Molecular Weight: 628.84
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source