Tamarixetin

Overview

Tamarixetin (4'-O-Methyl Quercetin) is an orally active natural flavonoid derivative of quercetin and caseinolytic protease p ( ClpP ) inhibitor with anti-inflammatory, antioxidant and antitumor effects. Tamarixetin inhibits the hydrolytic activity of ClpP to the fluorescent substrate Suc-LY-AMC with an IC 50 of 49.73 μM, which can be used for the study of Staphylococcus aureus infection . Tamarixetin inhibits tumor cell growth, induces apoptosis , and cell cycle arrest. Tamarixetin prevents cardiac hypertrophy by inhibiting the NFAT and AKT pathways.

Application

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Product Information

• Catalog No.: HY-N1181
• CAS No.: 603-61-2
• Molecular Formula: C16H12O7
• Molecular Weight: 316.26
• Purity: 98.80%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.5 mg/mL (7.90 mM); Clear solution
• Availability: In-stock

Source

Original product source