Aloenin aglycone

Overview

Aloenin aglycone (compound 13) is an NF-κB inhibitor that can be isolated from aloe exudate. Aloenin aglycone inhibits TNFα-induced NF-κB transcriptional activity ( IC 50 : 18.7 μM). Aloenin aglycone (10 μM) also reduced inducible nitric oxide synthase ( iNOS ) and intercellular adhesion molecule 1 (ICAM-1) gene expression after treatment of HepG2 cells with 10 ng/mL TNFα.

Application

Products | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > NF-κB | Products > Research Areas > Others | Products > Signaling Pathways > NO Synthase | Products > Signaling Pathways > NF-κB

Product Information

• Catalog No.: HY-N11996
• CAS No.: 59163-53-0
• Molecular Formula: C13H12O5
• Molecular Weight: 248.23
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source