Vismodegib (Standard) is the analytical standard of Vismodegib. This product is intended for research and analytical applications. Vismodegib (GDC-0449) is a BBB-permeable and orally active hedgehog pathway inhibitor with an IC 50 of 3 nM. Vismodegib also inhibits P-gp , ABCG2 with IC 50 values of 3.0 μM and 1.4 μM, respectively.
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