Casuarinin

Overview

Casuarinin is an orally active antiproliferative, anti-inflammatory, antifungal , virucidal and gastroprotective agent. Casuarinin upregulates the expression of p21/WAF1 , Fas/APO‑1 , mFasL , sFasL and HSP‑70 , arrests cell cycle, induces apoptosis and inhibits cancer cell proliferation. Casuarinin inhibits TNF‑α-induced phosphorylation of MAPK and activation of NF‑κB , downregulates the expression of iNOS , NF‑κB , COX‑2 and ICAM‑1 , and reduces the production of proinflammatory mediators. Casuarinin attenuates ethanol-induced activation of caspase‑3 and elevation of TNF‑α , inhibits the growth of Candida albicans , and inhibits HSV‑2 . Casuarinin can be used in research related to mammary adenocarcinoma, inflammatory skin diseases, gastric ulcers, candidiasis and herpes simplex virus infections.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Infection | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Viral Infection | Products > Disease Areas > Fungal Infection | Products > Disease Areas > Gastric Disease | Products > Disease Areas > Peptic Ulcer Disease | Products > Disease Areas > Breast Cancer | Products > Disease Areas > Skin Inflammation | Products > Disease Areas > HSV Infection | Products > Disease Areas > Candida Infection | Products > Disease Areas > Gastric Ulcer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Cytoskeleton | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Infection | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PAK | Products > Signaling Pathways > FASTK | Products > Signaling Pathways > HSP | Products > Signaling Pathways > p38 MAPK | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > NO Synthase | Products > Signaling Pathways > COX | Products > Signaling Pathways > HSV | Products > Signaling Pathways > Caspase | Products > Signaling Pathways > TNF Receptor | Products > Signaling Pathways > Fungal | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-N12717
• CAS No.: 79786-01-9
• Molecular Formula: C41H28O26
• Molecular Weight: 936.65
• Purity: 98.24%
• Storage: -20°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Availability: In-stock

Source

Original product source