T-Cadinol is a sesquiterpene isolated from C. sylvestris that exhibits anti- Trypanosoma cruzi activity, with IC 50 values of 18.2 μM and 15.8 μM against trypomastigote and amastigote forms, respectively. T-Cadinol can induce mitochondrial damage in parasites, leading to membrane hyperpolarization and decreased levels of reactive oxygen species . T-Cadinol can be used for the research of Chagas disease.
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