Axitinib

Overview

Axitinib (AG013736) is a tyrosine kinase inhibitor developed by Pfizer. Axitinib is a tyrosine kinase inhibitor that blocks the activation of VEGFR1, VEGFR2, VEGFR3, c-kit, and PDGFRβ (IC50 = 1.2, 0.25, 0.29, 1.7, and 1.6 nM, respectively). It has been shown to significantly inhibit growth of breast cancer in animal (xenograft) models.

Application

Products > Drug Discovery > Impurities > Anti-Neoplastic > Axitinib and Impurities | Products > Drug Discovery > Inhibitor

Product Information

• Catalog No.: B0084-461979
• CAS No.: 319460-85-0
• Molecular Formula: C22H18N4OS
• Molecular Weight: 386.5
• Purity: ≥98%
• Storage: -20°C Freezer
• Solubility: Soluble to 25 mM in DMSO.

Source

Original product source