Daclatasvir dihydrochloride (BMS-790052 dihydrochloride) is a potent and orally active HCV NS5A protein inhibitor with EC 50 s range of 9-146 pM for multiple HCV replicon genotypes . Daclatasvir dihydrochloride is also an organic anion transporting polypeptide 1B (OATP1B) and OATP1B3 inhibitor with IC 50 s of 1.5 μM and 3.27 μM, respectively.
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