Roseoside

Overview

Roseoside is an inhibitor of DNA gyrase and HAV 3C protease , and also inhibits HCV NS5A/B replicase in human systems with an IC 50 of 20 μM. Roseoside binds to the active site of enzymes and stabilizes the interaction by forming hydrogen bonds with key amino acid residues. Roseoside inhibits the growth of Gram-positive bacteria, Gram-negative bacteria, and Candida albicans , and interferes with HCV RNA replication in vitro by inhibiting HCV NS5A/B replicase ( IC 50 =20 μM). Roseoside shows no cytotoxicity and serves as a research tool for studies related to bacterial infections, candidiasis, HAV and HCV .

Application

Products | Products > Disease Areas > Hepatitis Virus Infection | Products > Disease Areas > Bacterial Infection | Products > Disease Areas > HCV NS5B Polymerase | Products > Disease Areas > Infection | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Infection | Products > Signaling Pathways > HCV | Products > Signaling Pathways > HCV Protease | Products > Signaling Pathways > DNA/RNA Synthesis | Products > Signaling Pathways > Bacterial

Product Information

• Catalog No.: HY-N1341
• CAS No.: 54835-70-0
• Molecular Formula: C19H30O8
• Molecular Weight: 386.44
• Purity: 96.99%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Availability: In-stock

Source

Original product source