FPL 62064 is a potent 5-lipoxygenase ( 5-LOX ) and COX dual inhibitor, with IC 50 values of 3.5 μM and 3.1 μM for RBL-1 cytosolic 5-lipoxygenase and prostaglandin synthetase (cyclooxygenase), respectively. FPL 62064 has potent anti-inflammatory activity.
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