Abecarnil (ZK 112119) is a ligand or a partial agonist for benzodiazepine (BZ) receptor . Abecarnil possesses anxiolytic and anticonvulsant properties. Abecarnil can act as a positive allosteric modulator of GABA A receptor . Abecarnil inhibits the binding of the BZ [3H]lormetazepam to rat cerebral cortex membranes, with an IC 50 of 0.82 nM. Abecarnil can be used for epilepsy research.
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