Gypsetin can inhibit acylcoenzyme A, cholesterol acyltransferase ( ACAT ) activity, inhibit rat liver microbody ACAT with an IC 50 of 18 μM, and its action is competitive with oleoyl-COA substrate, K i value is 5.5 μM. Gypsetin also inhibits Oleic acid from forming cholesterol esters with an IC 50 of 0.65 μM.
Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Acyltransferase
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